PEPTIDES
Peptide API Manufacturing
Peptide manufacturing combines demanding synthesis and purification processes with stringent requirements for product purity, contamination control and reliable fluid handling. Depending on the manufacturing route, processes may involve SPPS, LPPS or rDNA production followed by filtration, chromatography, ultrafiltration/diafiltration, lyophilization and final formulation.
Across these stages, Crane technologies help manage aggressive process media while supporting hygienic processing, cleanability and reliable process control.

SYNTHESIS
FILTRATION
REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (RP HPLC)
SIZE EXCLUSION CHROMATROGRAPHY
ULTRAFILTRATION/DIAFILTRATION UF/DF
MILLING & SIEVING
TABLETS PACKAGING & DISTRIBUTION
INJECTIONS PACKAGING & DISTRIBUTION
PEPTIDE: KEY SOLUTIONS
Synthesis & Corrosive Media
XOMOX lined valves together with RESISTOFLEX lined piping solutions for demanding chemical process conditions.
Purification
SAUNDERS aseptic diaphragm valves combined with lined flow-control technologies across chromatography, UF/DF and related purification stages.
Hygienic Processing
SAUNDERS aseptic technologies for process areas where purity, cleanability and contamination control are critical.
Automation & Monitoring
XOMOX actuation, SAUNDERS sensing and WESTLOCK valve monitoring technologies for reliable automated processes.

